The following article is designed to be a resource to The University of Iowa community for information and instruction pertaining to compatibility and system requirements for Microsoft Office 2016.
Is your computer ready to run Office 2016?
Find out the hardware and software requirements for Office 2016 on Microsoft's System Requirements for Office 2016 & Microsoft 365 page.

Office 2016 Mac Compatibility

Why can't I install Office 2016 on Windows 7, Windows XP or Windows Vista?
You’ll need a computer running Windows 8 and above to install Microsoft Office 2016. If you try to install Office 2016 with Windows XP or Windows Vista, it will not work. Consider upgrading to Windows 8 or above, or read more about Office 2016 requirements.
Can I use Office 2016 on my Macintosh computer?
Support for Office 2016 is will end on October 13, 2020 on Macintosh computers. Your Office 2016 applications will continue to function, will not disappear from your Mac nor will you lose any data. More information regarding this change in support can be found on Microsoft's End of Support for Office 2016 for Mac page.

Office 2016 For Mac Exchange Compatibility Chart

Does anyone know whether Office 2019 for Mac is compatible with Exchange 2016 Online Archive? If so, have you seen any documentation supporting this? I found this page, but it has not been updated for Office 2019 for Mac. May 20, 2019 The connection failure occurs because Outlook for Mac uses SSL to establish communication with an Exchange server. When SSL is disabled and secure renegotiation is implemented as defined in RFC 5746, Outlook requires the server to be in Compatible mode so that the session can be renegotiated from SSL to Transport Layer Security (TLS).

Office For Mac

1. The file uses a Visual Basic 6.0 control that does not work in 64-bit versions of Office or in 32-bit versions of Office that are running on a device that uses an ARM processor. Replace the control with a supported control if you want it to be available to Office applications in those environments. 10001: Office 2013: All Office 2013: Link.
2. Use Microsoft Office for Mac. Connect to Microsoft Exchange Server. Fun fact: There’s a version of Microsoft Office written just for Mac. So you can use Word, Excel, and PowerPoint on a Mac just like on a PC. MacOS also provides built-in support for the latest version of Microsoft Exchange Server.